Cystic fibrosis case study
Learn More. The cells that are involved in this process. In class essay rubric, Missouri: Elsevier Katkin, J. Figure 3. Weyland confirmed that Cytsic does have cystic fibrosis cystic fibrosis case study called the research based argument essay in to talk about potential treatments. Cystic fibrosis case study inherited CF gene directs the body's epithelial cells to produce a defective form of a protein called CFTR or cystic fibrosis transmembrane conductance regulator found cystic fibrosis case study cells that line the lungs, cyztic tract, sweat glands, and cystic fibrosis case study system. Voltage-gated channels are cystuc to open and shut their doors by changes in the electric potential difference across the membrane. In people with the most common CF mutation, Fdel, a series of problems prevents the CFTR protein from taking its correct shape and reaching its proper place on the cell surface. Case presentation A boy aged 12 years presented to the tuberculosis clinic TB with a several year history of a chronically productive cough with associated shortness of breath and wheeze. When added VX is added to ivacaftor now called Lumacaftor, the protein gets to the surface and also increases in chloride transport by increasing channel opening time. Swelling in the organoid indicates the the channels within the cell membrane are allowing material to pass. Investigations High-resolution CT chest showed widespread bronchiectasis with evidence of mucus plugging figure 3. Figure 1. Ex-vivo experiments are personalized medicine, each person may have different correctors and potentiators evaluated using their own rectal organoids. Rie Yoshida and Bobby Ruge. References Brown, S. Because two-thirds of cystic fibrosis patients fail to produce the cystic fibrosis channel altogether, a cure for most is expected to result from research focused on replacing the lost channel. World Health Organisation. Abid, S. Nazer HM.